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. Author manuscript; available in PMC: 2020 May 22.

Published in final edited form as: DNA Repair (Amst). 2018 Mar 30;65:64–72. doi: 10.1016/j.dnarep.2018.03.006

Table 2.

Comparisons of markers between smokers and non-smokers.

	Non-smoker participants (n = 31)	Smoker participants (n = 52)	p-value^a
DNA lesion (lesions/10⁶ DNA bases)
FapyAde	1.06±1.11	1.35±1.26	0.249
FapyGua	0.90±0.80	1.22±1.10	0.234
8-OH-Gua	6.30±4.44	5.15±3.12	0.484
8-OH-dG	8.38±3.77	8.32±5.59	1.000
5-OH-5-MeHyd	4.38±1.75	5.27±1.94	0.140
5-OH-Cyt	5.25±2.03	5.85±1.84	0.360
ThyGly	0.57±0.39	0.67±0.47	0.788
S-cdA	0.03±0.02	0.03±0.02	0.357

Malondialdehyde (μmol/L)	3.06±1.25	3.08±1.11	0.843

DNA glycosylases
OGG1 (ΔCt)	6.31±0.83	6.46±0.89	0.566
NEIL1 (ΔCt)	2.76±0.47	2.77±0.51	0.986

^a

Mann-Whitney U test.

Ct: cycle of threshold; ΔCt: the difference of Ct between target gene and β-actin (housekeeping) gene.