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. 2020 May 19;11(20):1816–1831. doi: 10.18632/oncotarget.27551

Figure 3. Inflammatory response in the tumor invasion front.

Figure 3

Student’s t-test showed no differences in the average number of leukocytes (A), neutrophils (C), mast cells (E) and lymphocytes (G) in the OSCCs from sham and PNT animals. PNT rats displayed increased average number of tumor-associated eosinophils (I) and macrophages (K) compared to sham animals. In both groups, tumor size was not associated with the average number of neutrophils (D) and mast cells (F) in the tumor invasion front. Advanced tumor-bearing PNT rats had higher average number of leukocytes (B), lymphocytes (H) and eosinophils in the invasive front (J). Early and advanced tumor-bearing PNT rats exhibited increased average number of macrophages in the tumor invasion front than sham-operated rats (L). * p < 0.05. Bars represent the mean ± SEM. * p < 0.05. ES: Early stage. AS: Advanced stage. (sham, n = 5; PNT, n = 11).