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LncRNA CCAT1 knockdown impaired colorectal cancer cell tumor growth in vivo. (A–C) The in vivo tumor formation assay suggested that CCAT1 knockdown dramatically reduced tumor size and weight in 5 samples of each group. (D) The expression of CCAT1 was downregulated in resected tumor tissues formed from CCAT1 knockdown. (E, F) Immunohistochemistry showed CCAT1 knockdown decreased the proliferation index Ki67 (×50). *P<0.05, **P<0.01, ***P<0.001, compared with NC group.
