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. 2020 May 13;12(9):8710–8727. doi: 10.18632/aging.103197

Figure 4.

Figure 4

Soy isoflavones could reduce apoptosis in hypothalamus of DIO male mice. (A) Quantification shows the mRNA levels of apoptosis factors in hypothalamus of DIO mice fed with basal diets and the addition with different doses of soy isoflavones; (B, C) Western blots and quantification show the apoptosis factors protein levels in hypothalamus of DIO mice fed with basal diets and the addition with different doses of soy isoflavones; (D, E) Western blots and quantification show the phosphorylation levels of AKT in hypothalamus of DIO mice fed with basal diets and the addition with different doses of soy isoflavones; (F) Quantification shows the mRNA levels of FAS and FASL in hypothalamus of DIO mice fed with basal diets and the addition with different doses of soy isoflavones; (G, H) Western blots and quantification show the protein levels of FAS and FASL in hypothalamus of DIO mice fed with basal diets and the addition with different doses of soy isoflavones; * p < 0.05, ** p < 0.01, ***p < 0.001.