Table 2. Enrichment analysis of module with genes related to major brain diseases.
| Disease | No. Disease Gene | Blue Module (795 genes) | Pink Module (278 genes) | Salmon Module (117 genes) | ||||||
| No. Overlapped Gene | P-value | Adjusted P Value | No. Overlapped Gene | P-value | Adjusted P Value | No. Overlapped Gene | P-value | Adjusted P Value | ||
| Intellectual Disability | 2684 | 132 | 6.00E-04 | 1.50E-03 | 49 | 1.01E-02 | 1.59E-02 | 22 | 3.63E-02 | 4.50E-02 |
| Epilepsy | 1643 | 98 | 2.93E-06 | 2.18E-05 | 43 | 1.04E-05 | 3.91E-05 | 15 | 3.68E-02 | 4.50E-02 |
| Autism | 1011 | 66 | 8.64E-06 | 3.70E-05 | 28 | 1.65E-04 | 4.96E-04 | 14 | 1.37E-03 | 2.74E-03 |
| ADHD | 411 | 23 | 3.75E-02 | 4.50E-02 | 11 | 2.03E-02 | 2.91E-02 | 9 | 4.64E-04 | 1.27E-03 |
| Bipolar Disorder | 850 | 45 | 1.29E-02 | 1.94E-02 | 25 | 1.51E-04 | 4.96E-04 | 13 | 8.37E-04 | 1.79E-03 |
| Depressive Disorder | 950 | 64 | 4.37E-06 | 2.18E-05 | 25 | 7.81E-04 | 1.79E-03 | 13 | 2.26E-03 | 3.99E-03 |
| Schizophrenia | 1965 | 115 | 9.21E-07 | 1.38E-05 | 50 | 3.88E-06 | 2.18E-05 | 28 | 2.19E-06 | 2.18E-05 |
| Alzheimer's Disease | 2061 | 123 | 1.25E-07 | 3.76E-06 | 36 | 4.64E-02 | 5.36E-02 | 22 | 1.89E-03 | 3.54E-03 |
| Parkinson' Disease | 409 | 22 | 5.85E-02 | 6.50E-02 | 8 | 1.71E-01 | 1.77E-01 | 6 | 2.60E-02 | 3.55E-02 |
| Glioma | 2389 | 115 | 2.89E-03 | 4.82E-03 | 39 | 8.85E-02 | 9.48E-02 | 11 | 7.80E-01 | 7.80E-01 |