Table 2. Comparison of the microstructural parameters of tibia from groups of rats.
Parameters | SHAM | OVX | OVX+BIBO3304 |
BV/TV (%) | 40.200±5.182 | 11.010±2.133* | 26.24±4.311*# |
Tb.N (mm-1) | 3.592±0.488 | 1.102±0.303* | 2.700±0.489*# |
Tb.Th (mm) | 0.099±0.010 | 0.068±0.006* | 0.093±0.008# |
Tb.Sp (mm) | 0.189±0.041 | 0.653±0.123* | 0.293±0.093# |
Conn.D (mm-3) | 122.300±15.89 | 22.790±7.899* | 78.530±12.680*# |
SMI | 1.331±0.373 | 2.515±0.161* | 1.915±0.285*# |
BV/TV, bone volume fraction; Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular spacing; Conn.D, connectivity density; SMI, structure model index. Data are expressed as mean ± SD (n = 6 in each group). *P<0.05 vs. SHAM, #P<0.05 vs. OVX by one-way ANOVA and Tukey’s post hoc test.