AF Patients (n=100) |
SHD (n= 47) |
NSHD (n= 53) |
p |
Age (years) (mean± SD) |
77.5 ± 9.3 |
70.4 ± 13.3 |
0.003 |
M/F |
27/20 |
27/26 |
0.515 |
Hypertension (n/%) |
40/85.1 |
44/83 |
0.776 |
Diabetes (n/%) |
16/34 |
18/33,4 |
0.642 |
Dyslipidaemia (n/%) |
18/38,3 |
17/32,1 |
0.515 |
Weight (Kg) (mean± SD) |
76.2 ± 13.9 |
74.2 ± 14.7 |
0.489 |
BMI (kg/m2) (mean± SD) |
27.4 ± 4.9 |
26.3 ± 4.4 |
0.248 |
SBP (mmHg) (mean± SD) |
127.0 ± 16.5 |
127.6 ± 14.8 |
0.863 |
DBP (mmHg) (mean± SD) |
70.4 ± 11.6 |
72.4 ± 9.2 |
0.331 |
Heart rate (bpm) (mean± SD) |
80.6 ± 16.9 |
79.5 ± 16.5 |
0.742 |
Echocardiographic findings |
|
|
|
Left atrium diameter (mm) (mean± SD) |
53.9 ± 6.9 |
38.9 ± 2.5 |
<0.0005 |
LVEF (%) (mean± SD) |
39.5 ± 4.4 |
60.0 ± 4.9 |
<0.0005 |
Cardiac diseases (n) |
|
|
|
Coronary heart disease |
29 |
|
|
Valvular diseases |
5 |
|
|
Diastolic dysfunction |
9 |
|
|
Dilatated Cardiomyopaty |
4 |
|
|
Total cholesterol (mMol/L) (mean± SD) |
136.5 ± 36.0 |
159.9 ± 40.7 |
0.003 |
LDL cholesterol (mMol/L) (mean± SD) |
78.5 ± 32.9 |
86.6 ± 33.5 |
0.225 |
Triglycerides (mmol/L) (mean± SD) |
82.7 ± 24.6 |
97.5 ± 50.1 |
0.069 |
HBa1C (mean± SD) |
6.4 ± 1.1 |
6.0 ± 1.2 |
0.079 |
Micro albuminuria (mean± SD) |
135.5± 208.2 |
60.2 ± 87.2 |
0.019 |
RHI (mean± SD) |
1.5 ± 0.4 |
2.0 ± 1.0 |
0.002 |
IL-18 pg/mL (mean± SD) |
477.2 ± 149.1 |
412.1 ± 186.7 |
0.059 |
sIL2Ralfa pg/mL (mean± SD) |
964.9 ± 334.6 |
782.4 ± 419.6 |
0.020 |
TNF-alfa pg/mL (mean± SD) |
8.6 ± 1.9 |
7.2 ± 3.7 |
0.021 |
ACE inhibitors or ARB (n/%) |
31/65,9 |
30/56,6 |
0.339 |
Beta blockade (n/%) |
29/61.7 |
21/39.6 |
0.028 |
Calcium channel blockers (n/%) |
9/19.14 |
17/32 |
0.141 |
Antiarrhythmic drugs (n/%) |
12/25.5 |
15/28.3 |
0.805 |
Antiplatels drugs (n/%) |
25/53.1 |
12/22.6 |
0.002 |
Anticoagulant drugs (n/%) |
27/57.4 |
26/49 |
0.401 |
Diuretic (n/%) |
31/65 |
18/33.9 |
0.001 |
Statin (n/%) |
18/38.3 |
16/30.2 |
0.393 |