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GDF11 treatment restores white matter integrity and synaptic plasticity at day 30 post-MCAo. (A) increase in MBP intensity in the CC and peri-infarct striatum, (B) increase in synaptophysin immunostaining, (C) decrease in GFAP+ cells in CC at day 30 post MCAo in aged mice. Magnification 20X. Scale bar 50μm. n=5-7. *p<0.05, **p<0.01.
