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. 2020 May 22;15(5):e0232459. doi: 10.1371/journal.pone.0232459

Table 2. Stepwise multivariate logistic regression analysis of the diagnosis of MDD and BD-I.

Variable Stepwise analysis
B S.E. p-value OR 95% CI
Cyclothymic temperament 3.68 0.87 0.000 39.52 7.14–218.75
Anxious temperament –2.44 0.88 0.005 0.09 0.02–0.49
YMRS score 0.13 0.06 0.049 1.13 1.00–1.28
Constant –2.79 0.99 0.005 0.06

Fit index of this model: χ2 = 28.11 (p-value < 0.05), Cox-Snell R2 = 0.11, Hosmer–Lemeshow test p = 0.275, sensitivity = 0.17, specificity = 0.96, positive predictive value = 0.56, negative predictive value = 0.78, AUC of ROC = 0.71

dependent variable: the diagnosis of MDD (1) and BD-I (2)

7 independent variables: scores of 5 subscales of the TEMPS-A and the severity of depressive and manic symptoms (PHQ-9 and YMRS scores, respectively).

AUC, area under the curve; BD- I, bipolar I disorder; CI, confidence interval; MDD, major depressive disorder; OR, odds ratio; PHQ-9, Patient Health Questionnaire-9; ROC, receiver-operating characteristic; B, partial regression coefficient; S.E., standard error; TEMPS-A, Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire; YMRS, Young Mania Rating Scale.