Table 3. Random survival forest method, C-index and number of radiomic or (non)-treatment related prognostic clinical factors.
| C-index Prognostic (No. feat) | C-index Treatment (No. feat) | C-index GTVprim (No. feat) | C-index TB 3mm (No. feat) | C-index TB 5mm (No. feat) | C-index GTVprim, + TB 3mm + TB 5mm (No. feat) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Train | Val | Train | Val | Train | Val | Train | Val | Train | Val | Train | Val | |
| Oropharynx | ||||||||||||
| Clinical-OS | 0.74 (5) | 0.74 (5) | 0.52 (1) | 0.53 (1) | ||||||||
| Clinical-LR | 0.81 (5) | 0.81 (5) | 0.51 (1) | 0.51 (1) | ||||||||
| Clinical-DM | 0.85 (4) | 0.85 (4) | 0.51 (1) | 0.52 (1) | ||||||||
| Radiomics-OS | 0.73 (3) | 0.58 (3) | 0.77 (6) | 0.49 (6) | 0.79 (5) | 0.60 (5) | 0.78 (6) | 0.61 (6) | ||||
| Radiomics-LR | 0.77 (2) | 0.49 (2) | 0.83 (3) | 0.43 (3) | 0.83 (2) | 0.59 (7) | 0.71 (3) | 0.57 (3) | ||||
| Radiomics-DM | 0.82 (2) | 0.49 (2) | 0.91 (8) | 0.55 (8) | 0.81 (3) | 0.50 (3) | 0.86 (4) | 0.32 (4) | ||||
| All subsites | ||||||||||||
| Clinical-OS | 0.77 (7) | 0.77 (7) | 0.56 (1) | 0.51 (1) | ||||||||
| Clinical-LR | 0.79 (3) | 0.79 (3) | 0.56 (2) | 0.49 (2) | ||||||||
| Clinical-DM | 0.84 (4) | 0.84 (4) | - | - | ||||||||
| Radiomics-OS | 0.79 (7) | 0.58 (4) | 0.89 (4) | 0.58 (4) | 0.77 (5) | 0.60 (5) | 0.78 (6) | 0.59 (6) | ||||
| Radiomics-LR | 0.81 (3) | 0.52 (2) | 0.80 (2) | 0.52 (2) | 0.86 (7) | 0.59 (7) | 0.83 (2) | 0.53 (2) | ||||
| Radiomics-DM | 0.86 (3) | 0.49 (3) | 0.86 (4) | 0.49 (4) | 0.96 (3) | 0.50 (3) | 0.86 (3) | 0.43 (3) | ||||
Abbreviations GTVprim—Primary Gross Tumor Volume, OS- Overall Survival, LR- Locoregional Recurrence, DM- Distant Metastasis.