Table 2. Incidence and degree of chimerism after BMT according to TBI dosage and MHC disparity.
TBI | MHC | BMT | Chimerism | Death | |||
---|---|---|---|---|---|---|---|
dosage (Gy) | disparity | n | incidence | % | n | ||
day 30 | day 100 | day 30 | day 100 | ||||
10 | Complete | 16 | 15 / 15 | 12 / 12 | 91 +/- 4 | 90 +/- 2 | 4 |
Class II | 20 | 18 / 18 | 15 / 15 | 87 +/- 7 | 81 +/- 4 | 5 | |
Class I | 18 | 18 / 18 | 18 / 18 | 93 +/- 3 | 95 +/- 2 | - | |
None | 10 | 10 / 10 | 10 / 10 | 94 +/- 4 | 93 +/- 2 | - | |
8 | Complete | 18 | 6 / 18 | 3 / 15 | 39 +/- 28 | 10 +/- 6 | 3 |
Class II | 9 | 4 / 9 | 2 / 7 | 42 +/- 27 | 12 / 23 | 2 | |
Class I | 10 | 9 / 10 | 8 / 10 | 58 +/- 19 | 65 +/- 27 | - | |
None | 6 | 6 / 6 | 6 / 6 | 84 +/- 8 | 87 +/- 5 | - | |
6 | Complete | 6 | 0 / 6 | 0 / 6 | - | - | - |
Class II | 6 | 0 / 6 | 0 / 6 | - | - | - | |
Class I | 6 | 2 / 6 | 1 / 6 | 16 +/- 3 | 13 | - | |
None | 8 | 8 / 8 | 8 / 8 | 63 +/- 5 | 68 +/- 7 | - | |
No TBI | None | 6 | 0 / 0 | 0 / 0 | - | - |
BMT, bone marrow transplantation; MHC, Major histocompatibility complex.