Table 4. MHC (RT1) immunogenetics of strain combinations for heart transplantation.
| MHC match (Heart to BM recipient or donor) | MHC region | ||||
|---|---|---|---|---|---|
| Strain combinations | RT1A | RTA1B/D | RT1C/E | ||
| (class I) | (class II) | (class I) | |||
| complete (recipient) | Recipient | LEW.1A | a | a | a |
| BM donor | LEW.1W | u | u | u | |
| Heart donor | LEW.1A | a | a | a | |
| complete (donor) | Recipient | LEW.1A | a | a | a |
| BM donor | LEW.1W | u | u | u | |
| Heart donor | LEW.1W | u | u | u | |
| class II (donor) | Recipient | LEW.1AR2 | a | a | u |
| BM donor | LEW.1AR1 | a | u | u | |
| Heart donor | LEW.1WR1 | u | u | a | |
| class I (donor) | Recipient | LEW.1WR1 | u | u | a |
| BM donor | LEW.1AR1 | a | u | u | |
| Heart donor | LEW.1AR2 | a | a | u | |
| 3rd party | Heart donor | Brown Norway | n | n | n |
BM, bone marrow; MHC, Major histocompatibility complex. Matched MHC loci of heart and BM recipients and donors, respectively, are shown in bold and underlined.