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. 2020 May 22;15(5):e0233503. doi: 10.1371/journal.pone.0233503

Table 1. Diverse base editing events generated at T2 generation using EC promoter.

T1 lines T2 genotype Editing ratio
1# CCGATGATCCCGAGTGGTGGCAC 2/6
CCGATGATCCCRAGTGRTRGCAC 1/6
CCGATGATCCCGAGTGGTRGCAC 3/6
2# CCGATGATCCCGAGTGGTGGCAC 5/12
CCGATGATCCCGAGTGGTRGCAC 3/12
CCGATGATCCCGAGTGRTGGCAC 1/12
CCGATGATCCCGAGTGRTRGCAC 2/12
CCGATGATCCCGAGTGRTAGCAC 1/12
3# CCGATGATCCCGAGTGGTGGCAC 15/18
CCGATGATCCCGAGTRRTGGCAC 1/18
CCGATGATCCCGAGTGRTRGCAC 1/18
CCGATGATCCCRAGTRGTGGCAC 1/18
4# CCGATGATCCCGAGTGGTGGCAC 12/14
CCGATGATCCCGAGTGGTRGCAC 1/14
CCGATGATCCCGAGTGRTRGCAC 1/14

R in red stands for the heterozygosity of base A and G. A in red is homozygous edits. 5’CCG3’ in blue is PAM.