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. 2020 May 18;13:4319–4337. doi: 10.2147/OTT.S243823

Table 1.

The Relationship Between H2AFZ, H2AFV and HCC Clinical Features

Clinicopathological Parameters N H2AFZ Expression P-value H2AFV Expression P-value
Age ≤50 78 50.53 ± 36.35 0.079 22.66 ± 9.49 0.18
>50 292 43.66 ± 28.88 21.23 ± 8.05
Gender Female 121 46.60 ± 29.44 0.54 22.89 ± 8.49 0.028*
Male 250 44.50 ± 31.29 20.86 ± 8.25
Child–Pugh grade A 217 42.11 ± 26.63 0.37 20.75 ± 7.72 0.39
B+C 22 36.81 ± 22.01 19.29 ± 6.36
AFP ≤200 201 38.69 ± 23.99 1.6x10−4* 20.19 ± 7.31 0.014*
>200 77 54.64 ± 32.47 22.78 ± 7.87
Grade G1 55 34.15 ± 23.56 0.000008* 20.50 ± 8.89 0.032*
G2 177 41.25 ± 26.57 20.45 ± 7.53
G3 122 54.02 ± 36.40 23.02 ± 8.95
G4 12 66.15 ± 26.75 24.00 ± 8.42
Cancer status Tumor free 234 44.49 ± 32.15 0.91 21.10 ± 8.68 0.21
With tumor 110 44.88 ± 28.09 22.32 ± 7.69
Pathologic stage I 171 37.53 ± 23.83 0.000006* 19.92 ± 7.08 0.001*
II 86 50.33 ± 34.69 22.39 ± 8.29
III 85 56.88 ± 35.48 24.04 ± 10.24
IV 5 32.35 ± 9.22 17.48 ± 7.85
T classification T1 181 37.47 ± 24.05 0.000013* 19.83 ± 7.13 0.001*
T2 94 50.86 ± 33.76 22.91 ± 8.40
T3 80 54.69 ± 35.40 23.70 ± 10.03
T4 13 58.46 ± 33.71 22.22 ± 9.78
N classification N0 252 45.82 ± 31.59 0.51 21.81 ± 8.73 0.76
N1 4 59.28 ± 24.51 23.16 ± 10.80
M classification M0 266 46.17 ± 31.94 0.49 21.77 ± 8.55 0.45
M1 4 35.06 ± 8.02 18.48 ± 8.69
Vascular tumor cell None 206 40.03 ± 25.60 0.10 21.02 ± 8.27 0.81
Micro 93 45.66 ± 29.60 21.64 ± 8.25
Macro 16 51.21 ± 30.92 20.66 ± 7.42
Vital status Alive 206 40.03 ± 25.60 0.095 21.02 ± 8.27 0.55
Dead 93 45.66 ± 29.60 21.64 ± 8.25

Notes: *P<0.05. AFP: alpha fetoprotein.