Table 2.
Incidences and rates of cardiovascular outcomes at 4‐years
| All N = 77,752 events/100PY (95% CI) n (%) | Total established disease N = 36,398 events/100PY (95% CI) n (%) | Any coronary artery diseasea N = 20,468 events/100PY (95% CI) n (%) | Any cerebrovascular diseasea N = 10,128 events/100PY (95% CI) n (%) | Any peripheral artery diseasea N = 13,256 events/100PY (95% CI) n (%) | Multiple risk factors only N = 41,354 events/100PY (95% CI) n (%) | |
|---|---|---|---|---|---|---|
| MACE | 2.95 (2.88‐3.01) | 3.60 (3.49‐3.71) | 3.58 (3.43‐3.72) | 4.41 (4.19‐4.65) | 3.70 (3.52‐3.89) | 2.41 (2.33‐2.49) |
| 7699 (9.9) | 4239 (11.6) | 2369 (11.6) | 1416 (14.0) | 1554 (11.7) | 3460 (8.4) | |
| Myocardial infarctionb | 1.34 (1.30‐1.38) | 1.73 (1.66‐1.81) | 2.07 (1.96‐2.18) | 1.49 (1.37‐1.63) | 1.84 (1.71‐1.97) | 1.02 (0.97‐1.07) |
| 3562 (4.6) | 2081 (5.7) | 1393 (6.8) | 496 (4.9) | 787 (5.9) | 1481 (3.6) | |
| Ischemic strokeb | 1.71 (1.67‐1.76) | 1.98 (1.90‐2.06) | 1.60 (1.50‐1.69) | 3.30 (3.11‐3.50) | 1.88 (1.75‐2.01) | 1.49 (1.43‐1.56) |
| 4543 (5.8) | 2380 (6.5) | 1084 (5.3) | 1072 (10.6) | 803 (6.1) | 2163 (5.2) | |
| Cardiovascular‐related death† | 0.47 (0.44‐0.49) | 0.55 (0.51‐0.59) | 0.51 (0.46‐0.56) | 0.65 (0.57‐0.74) | 0.63 (0.56‐0.71) | 0.40 (0.37‐0.43) |
| 1257 (1.6) | 673 (1.8) | 350 (1.7) | 221 (2.2) | 276 (2.1) | 584 (1.4) |
a
These cohorts overlap each other.
b
Outcomes are not mutually exclusive.
Abbreviations: CI, confidence interval; MACE, major adverse cardiovascular events; PY, person‐years.