Table 1.
Patient characteristics
| Test cohort (n = 167) | Validation cohort (n = 100) | P‐value | |
|---|---|---|---|
| Age (years) | 61 ± 13 | 48 ± 8 | <.001 |
| Female, n (%) | 123 (74%) | 70 (70%) | .49 |
| Length (m) | 1.67 ± 0.1 | 1.71 ± 0.1 | .84 |
| Weight (kg) | 110 ± 15 | 127 ± 18 | .27 |
| BMI (kg/m2) | 39 ± 4 | 43 ± 4 | .20 |
| BSA (m2) | 2.3 ± 0.2 | 2.5 ± 0.2 | <.001 |
| Systolic BP (mmHg) | 147 ± 25 | 142 ± 21 | .09 |
| Diastolic BP (mmHg) | 76 ± 12 | 80 ± 12 | .51 |
| Heart rate (beats/min) | 78 ± 16 | 71 ± 13 | .048 |
| Diabetes mellitus, n (%) | 112 (67%) | 21 (21%) | <.001 |
| Hypertension, n (%) | 80 (48%) | 31 (31%) | .008 |
| Left axis deviation, n (%) | 16 (10%) | 5 (5%) | .22 |
| RaVL + SV3 (mm) (Cornell voltage) | 11.8 ± 6 | 9.6 ± 5 | .002 |
| SV1 + RV5/RV6 (mm) (Sokolow‐Lyon index) | 15.9 ± 6 | 15.7 ± 6 | .81 |
| SV4 + Sdeepest (mm) (Peguero‐Lo Presti criteria) | 14.5 ± 5 | 12.1 ± 6 | .001 |
| LVM (g) | 197 ± 67 | 196 ± 63 | .83 |
| LVM abnormal, n (%) | 121 (72%) | 69 (69%) | .63 |
| LVMI (g/m2) | 94 ± 81 | 79 ± 22 | .13 |
| LVMI abnormal, n (%)a | 53 (32%) | 19 (19%) | .026 |
Note: Values represent mean ± SD or n (%).
Abbreviations: BMI, body mass index; BP, blood pressure; BSA, body surface area; LVM, left ventricular mass; LVMI, left ventricular mass index.
a
Used as the definition for LVH as defined by echocardiography.