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. 2020 May 14;13:4157–4168. doi: 10.2147/OTT.S246710

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© 2020 Yu et al.

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miR-3714 represses the in vivo migration of bladder cancer cells by targeting the 3’UTR of ADAM15. Patient-derived bladder cancer cell lines – transducted with the control, miR-3174 and miR-3174 + ADAM15^mut (ADAM15 with the mutated binding site of miR-3174 in 3’UTR) – were injected into a subcutaneous position in nude SCID mice. The results are shown as (A) images of the tumor tissue, (B) tumor volumes, (C) inhibition rate calculated by tumor volumes, (D) tumor weights, and (E) inhibition rates calculated from the tumor weights. *P < 0.05.