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. 2020 May 18;14:1897–1908. doi: 10.2147/DDDT.S252626

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© 2020 Cheng et al.

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Leflunomide induced cell cycle arrest in S phase in bladder cancer cells. 5637 (A, B) and T24 (C, D) cells were treated with DMSO or rising concentrations of leflunomide (12.5–200μM) for 48 hours, the cell phase populations were determined by ﬂow cytometry with PI labeling. The results (B, D) represent the mean ± SD from three independent experiments.