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. 2020 May 22;10:8573. doi: 10.1038/s41598-020-65591-z

Table 2.

Summary of meta-analyses.

Endpoint HR/OR (95% CI) P-value No. of studies
EFS 1.01 (0.92, 1.11) 0.78 20
1-year EFS 0.83 (0.67, 1.02) 0.07 19
3-year EFS 1.05 (0.92, 1.20) 0.47 19
5-year EFS 1.06 (0.91, 1.23) 0.46 19
OS 1.02 (0.92, 1.14) 0.66 13
1-year OS 0.99 (0.75, 1.30) 0.92 13
3-year OS 1.00 (0.84, 1.19) 1.00 13
5-year OS 1.02 (0.89, 1.17) 0.75 13
RR 1.16 (0.81, 1.66) 0.40 11
AEs, overall 1.02 (0.59, 1.74) 0.95 10
Nausea/vomiting 0.56 (0.27, 1.16) 0.12 4
Leukopenia 0.82 (0.40, 1.68) 0.58 9

Abbreviations: AE, adverse event; CI, confidence interval; EFS, event-free survival; HR, hazard ratio; OR, odds ratio; OS, overall survival; RR, response rate.