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. 2020 May 22;11:2567. doi: 10.1038/s41467-020-16427-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Concentration and size distribution of NPs in human serum samples. b Concentration and size distribution of NPs in human PE samples. c Comparison of particle concentrations in serum and PE. ^*P = 0.0002 (unpaired Student’s two-tailed t test). Error bars represent mean ± s.d. (n = 37). d Correlation of particle concentration in PE with the age. P = 0.84 (F test in linear regression analysis; n = 37). e–f Elemental concentration ranges e and heating map f of normalized elemental fingerprints of the NPs extracted from 37 human PE samples (n = 37). In e bounds of the box spans from 25% to 75% percentile, center line represents median, and whiskers visualize 5% and 95% of the data points. The high-abundance elements in organisms (e.g., C, H, O, N, S, P, Na, K, Ca, Mg, and Cl) are not shown. Source data are provided as a Source Data file.