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. 2020 May 22;3:259. doi: 10.1038/s42003-020-0985-2

Fig. 4. Transcriptional markers of disease resilience.

Fig. 4

Macrophage gene expression over time plotted for samples obtained on days of life 1, 7, 14, and 21 from patients resilient to BPD (no BPD or mild BPD) and those developing severe BPD. a Increased expression of MRC1 after day 1 of life in patients either not developing BPD or only developing mild disease. b–h Genes with similar time-dependent patterns of expression in resilient patients compared to severe BPD patients. Genes were identified by differential expression comparison between day 1 and later time points, as well as using the “Correlation” function within Hegemon. (For severe BPD, n = 25 on day 1, n = 14 on day 7, n = 9 on day 14, n = 4 on day 21; for none/mild BPD, n = 13 on day 1, n = 5 on day 7, n = 4 on day 14, n = 3 on day 21).