Table 2.
Comparison of thickness and volume of the entire retina and of individual retinal layers between healthy subjects and patients with mitochondrial disease (mean ± SD).
| RT | RNFL | GCL | IPL | INL | OPL | ONL | IRL | PR | RPE | |
|---|---|---|---|---|---|---|---|---|---|---|
| Retinal layers thickness | ||||||||||
| Mitochondrial disease | 304 ± 6 | 13.3 ± 0.9 | 19.5 ± 3.7 | 23.7 ± 2.1 | 23.3 ± 2.7 | 25.9 ± 1.3 | 84.8 ± 3.6 | 190.3 ± 8.7 | 88.2 ± 1.2 | 16.4 ± 3.8 |
| Controls | 313 ± 4 | 13.4 ± 0.3 | 18.3 ± 1.5 | 21.3 ± 0.9 | 21.1 ± 1.4 | 25.5 ± 1.1 | 93.3 ± 2.9 | 191.1 ± 4.5 | 87.3 ± 0.9 | 17.8 ± 3.2 |
| P | 0.21 | 0.96 | 0.77 | 0.32 | 0.42 | 0.82 | 0.08 | 0.94 | 0.57 | 0.33 |
| Retinal layers volume | ||||||||||
| Mitochondrial disease | 0.73 ± 0.02 | 0.010 ± 0.0 | 0.016 ± 0.002 | 0.019 ± 0.002 | 0.018 ± 0.002 | 0.019 ± 0.001 | 0.067 ± 0.002 | 0.14 ± 0.004 | 0.068 ± 0011 | 0.014 ± 0.002 |
| Controls | 0.89 ± 0.03 | 0.011 ± 0.0 | 0.013 ± 0.001 | 0.018 ± 0.001 | 0.018 ± 0.001 | 0.020 ± 0.0 | 0.074 ± 0.002 | 0.15 ± 0.013 | 0.069 ± 0.001 | 0.015 ± 0.002 |
| P | 0.0002 | 0.34 | 0.40 | 0.53 | 0.96 | 0.34 | 0.03 | 0.30 | 0.52 | 0.22 |