Table 2.
Frequencies of isolated genotypes of KLOTHO SNPs C1818T, G395A, and C370S in the patient groups with Myocardial Infarction, Stroke and Vascular Calcification at baseline.
| C1818T (rs564481) | Myocardial Infarction | Stroke | Vascular calcification | |||
|---|---|---|---|---|---|---|
| n (%) | p value | n (%) | p value | n (%) | p value | |
| CC | 5 (1.7) | 0.006 | 18 (6.2) | 0.791 | 163 (64.2) | 0.661 |
| CT | 17 (6.7) | 11 (4.3) | 144 (63.2) | |||
| TT | 5 (8.3) | 1 (1.7) | 39 (69.6) | |||
| Allele C | 22 (4.1) | 0.130 | 29 (3.4) | 0.649 | 307 (63.7) | 0.379 |
| Allele T | 22 (7.0) | 0.002 | 12 (3.8) | 0.543 | 183 (64.4) | 0.949 |
| G395A (rs1207568) | ||||||
| GG | 18 (4.4) | 0.758 | 26 (6.4) | 0.455 | 242 (66.5) | 0.285 |
| GA | 8 (4.4) | 4 (2.2) | 98 (59.4) | |||
| AA | 1 (9.1) | 0 (0) | 6 (66.7) | |||
| Allele G | 26 (4.4) | 0.457 | 30 (5.1) | 0.899 | 340 (64.4) | 0.882 |
| Allele A | 9 (4.6) | 0.905 | 4 (2.1) | 0.133 | 104 (59.8) | 0.128 |
| C370S (rs9527025) | ||||||
| CC | 21 (4.5) | 0.992 | 20 (4.3) | <0.001 | 270 (65.5) | 0.468 |
| CS | 6 (4.0) | 9 (6.8) | 74 (59.7) | |||
| SS | 0 (0) | 0 (0) | 1 (100.0) | |||
| Allele C | 27 (4.5) | 0.706 | 29 (4.9) | 0.984 | 344 (64.3) | 0.932 |
| Allele S | 6 (4.5) | 0.992 | 9 (7.5) | 0.246 | 75 (60.3) | 0.285 |
Data expressed as absolute frequency (n) and percentage (%)
Analysed by Pearson χ2.