. 2020 May 22;10:8578. doi: 10.1038/s41598-020-65603-y

Table 3.

Incidence rate of PTB per 100000 person-years among T2DM patients by subgroups.

	All subjects					Men					Women
	No. of T2DM patients	Person years	No. of PTB cases	Incidence rate (1/100000)	P value*	No. of T2DM patients	Person years	No. of PTB cases	Incidence rate (1/100000)	P value*	No. of T2DM patients	Person years	No. of PTB cases	Incidence rate (1/100000)	P value*
Overall	240 692	855782	439	51.3		110262	389713	336	86.2		130 430	466069	103	22.1
Age group (years)					<0.001					0.027					0.121
35–44	7779	29150	23	78.9		4841	17937	17	94.8		2938	11213	6	53.5
45–54	42 250	163970	112	68.3		20 571	78761	90	114.3		21 679	85209	22	25.8
55–64	89 934	322037	157	48.8		40 610	144765	117	80.8		49 324	177272	40	22.6
65–74	60 309	207232	93	44.9		27 700	94633	74	78.2		32 609	112599	19	16.9
75–	40 420	133393	54	40.5		16 540	53617	38	70.9		23 880	79776	16	20.1
BMI (kg/m²) ^a					<0.001					<0.001					<0.001
<18.5	3491	12548	27	215.2		2140	4752	21	442.0		1351	7796	6	77.0
18.5–24.9	139 819	496125	321	64.7		74 468	230843	252	109.2		65 351	265281	69	26.0
≥25.0	91 108	329073	85	25.8		50 530	145608	58	39.8		40 578	183465	27	14.7
Central obesity ^b					<0.001					<0.001					0.010
Yes	100 940	367961	132	35.9		42 155	154020	97	63.0		58 785	213941	35	16.4
No	128 844	458011	294	64.2		62 730	220968	228	103.2		66 114	237042	66	27.8
High blood pressure ^c					0.573					0.841					0.106
Yes	45 833	159765	78	48.8		22 311	77590	66	85.1		23 522	82175	12	14.6
No	191 071	683430	357	52.2		86 145	306171	267	87.2		104 926	377259	90	23.9
FPG (mmol/L) ^d					<0.001					<0.001					0.245
<4.4	554	2017	1	49.6		271	1000	1	100.0		283	1018	0	0
4.4–5.9	29 235	113187	47	41.5		12 652	48308	33	68.3		16 583	64879	14	21.6
6.0–7.9	152 066	541679	260	48.0		68 481	243693	200	82.1		83 585	297985	60	20.1
8–9.9	26 188	87119	51	58.5		12 744	42131	39	92.6		13 444	44988	12	26.7
≥10	9956	30031	43	143.2		5307	15753	36	228.5		4649	14277	7	49.0
Interval between diagnosis and registry (years) †					0.378					0.569					0.353
<0.5	92 954	231161	115	49.8		42 660	104721	88	84.0		50 294	126440	27	21.4
0.5–0.9	34 267	119121	65	54.6		14 973	51336	51	99.4		19 294	67786	14	20.7
1–1.4	27 901	100759	50	49.6		12 817	45836	41	89.5		15 084	54922	9	16.4
1.5–1.9	19 589	85666	54	63.0		8876	38509	38	98.7		10 713	47158	16	33.9
≥2	65 981	319074	155	48.6		30 936	149311	118	79.0		35 045	169763	37	21.8

Abbreviation: T2DM, type 2 diabetes; PTB, pulmonary tuberculosis; BMI, body mass index; FPG, fasting plasma glucose.

*P values were calculated using a Log-rank test.

^†Referring to interval between date of diagnosis of T2DM and date of registration in Shanghai Standardized Diabetes Management System.

^a6274 missing values excluded from analysis; ^b10908 missing values excluded from analysis; ^c3788 missing values excluded from analysis; ^d22693 missing values excluded from analysis.