Table 3.
Frequency of micronuclei (MN), cytokinesis-block proliferation index (CBPI) and cytostasis (Cyt) in A549 and Raw 267.4 cell lines either untreated (Ctr) or exposed to asbestos (D) or to slags powder of varying granulometries (A < 10 µm, B < 5 µm, C < 2 µm).
| Cell lines | Sample (15.62 µg/cm2) | MN/1000 cells | CBPI | Cyt % |
|---|---|---|---|---|
| A549 cells | Ctr | 1.81 | 1.87 ± 0.15 | — |
| A | 2.98 | 1.88 ± 0.08 | 1.15 | |
| B | 3.01 | 1.87 ± 0.07 | 0 | |
| C | 3.20 | 1.88 ± 0.13 | 1.15 | |
| D | 9.59a | 2.03 ± 0.05 | 18.39 | |
| RAW 246.7 | Ctr | 0.82 | 1.64 ± 0.09 | — |
| A | 0.84 | 1.65 ± 0.10 | 1.56 | |
| B | 0.88 | 1.66 ± 0.12 | 3.21 | |
| C | 1.60 | 1.71 ± 0.11 | 10.94 | |
| D | 7.60a | 1.83 ± 0.05 | 29.69 |
Statistical analysis: aP < 0.05 vs. control.