Table 3.
Maternal and neonatal outcomes of sPTB and pi-PTB compared to full term births.
| Characteristics | sPTB | RR [95% CI] | pi-PTB | RR [95% CI] | TermBirths |
|---|---|---|---|---|---|
| Onset of labor | |||||
| Spontaneous labour | 65 (83.3%) | Ref. | 0 (0%) | Ref. | 617 (59.3%) |
| PROM + induction | 9 (11.5%) | 1.66 [0.69–3.95] | 0 (0%) | — | 48 (4.6%) |
| Induction intact membranes | 0 (0%) | — | 6 (12.8%) | — | 184 (17.7%) |
| Elective C-section | 4 (5.2%) | 0.22 [0.03–1.50] | 41 (87.2%) | — | 191 (18.4%) |
| Mode of delivery | |||||
| Vaginal | 57 (73.1%) | Ref. | 4 (8.5%) | Ref. | 556 (53.8%) |
| Intrapartum C-section | 5 (6.4%) | 0.65 [0.36–1.16] | 1 (2.1%) | 0.56 [0.02–20.32] | 277 (23.8%) |
| Elective C-section | 16 (20.5%) | 0.23 [0.05–1.14] | 42 (89.4%) | 21.73 [2.60–181.80] | 251 (24.1%) |
| Length of maternal postpartum hospitalizationa | |||||
| 1–3 days | 62 (79.5%) | Ref. | 28 (59.6%) | Ref. | 951 (91.5%) |
| 4–6 days | 13 (16.7%) | 2.44 [1.12–5.33] | 13 (27.7%) | 5.22 [1.05–25.89 | 74 (7.1%) |
| ≥7 days | 3 (3.8%) | 2.88 [0.64–12.90] | 6 (12.8%) | 10.49 [2.34–47.10] | 14 (1.3%) |
| Preeclampsia | 2 (2.6%) | 0.40 [0.07–2.18] | 18 (38.3%) | 7.32 [3.15–16.99] | 67 (6.4%) |
| HIPb | 12 (16.9%) | 1.15 [0.39–3.44] | 5 (12.5%) | 0.83 [0.27–2.51] | 133 (14.8%) |
| Mean (±SD) birthweight (g)c | 2,253 ± 666.9 | 1,002 [893.6–1111.0]# | 1,824 ± 845.7 | 1,431 [921.9–1940.0]# | 3,255 ± 422.3 |
| Adequacy of birthweight to GAc | |||||
| SGA (p < 10) | 8 (10.2%) | 0.94 [0.20–4.49] | 45 (44.7%) | 5.40 [2.39–12.21] | 117 (11.4%) |
| AGA (p10–90) | 58 (74.4%) | Ref. | 23 (48.9%) | Ref. | 793 (77.2%) |
| LGA (p > 90) | 12 (15.4%) | 1.36 [0.48–3.86] | 3 (6.4%) | 0.89 [0.14–5.65] | 117 (11.4%) |
| Fetal death | 1 (1.3%) | 14.51 [10.63–19.79] | 2 (4.3%) | 24.11 [18.88–30.79] | 0 (0%) |
| Neonatal death | 2 (2.6%) | 9.90 [5.08–19.32] | 5 (10.6%) | 22.48 [10.99–45.99] | 1 (0.1%) |
| Apgar score – 5th minute < 7d | 5 (6.8%) | 5.47 [2.46–12.15] | 5 (11.1%) | 9.04 [3.51–23.31] | 9 (0.9%) |
| Need of intubation after birthe | 12 (15.4%) | 12.42 [8.85–17.43] | 10 (22.2%) | 21.67 [11.79–39.85] | 4 (0.4%) |
| NICU admission | 40(51.3%) | 7.54 [3.65–15.58] | 36 (76.6%) | 23.47 [16.13–34.16] | 97 (9.3%) |
| Phototherapy for jaundicee | 47 (61.0%) | 7.08 [3.68–13.60] | 31 (68.9%) | 10.68 [5.66–20.14] | 154 (14.9%) |
| Length of NICU stay (days) | |||||
| 1–3 days | 4 (10.0%) | Ref. | 8 (22.2%) | Ref. | 59 (60.8%) |
| 4–6 days | 5 (12.5%) | 3.58 [0.54–23.81] | 3 (8.3%) | 1.26 [0.13–12.34] | 17 (17.5%) |
| ≥7 days | 31 (77.5%) | 9.39 [1.73–51.06] | 25 (69.4%) | 4.55 [1.39–14.92] | 21 (21.6%) |
| Neonatal sepsisf | 14 (18.4%) | 7.17 [4.54–11.33] | 10 (21.7%) | 9.76 [3.88–24.54] | 20 (1.9%) |
| APO* g [95%CI] | 37 (50.0% [38.0–62.0%]) | 7.17 [3.16–16.28] | 38 (80.9% [63.0–91.3%]) | 29.13 [18.07–46.98] | 92 (9.4% [3.1–25.4%]} |
| Total | 78 | 47 | 1,040 | ||
Missing information for: a1; b157; c13; d65; e11; f5; g64. #WMD, weighted mean difference [95% CI]. *APO: NICU stay >7 days or intubation at birth or Apgar score <7 at 5 minutes or fetal/neonatal death or discharge home on oxygen or neonatal sepsis or cyanosis or hypoglycaemia or birth asphyxia or respiratory distress or mechanical ventilation.