Table. 3.
Univariate and multivariate analysis of risk factors for patients’ overall survival (OS).
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| χ2 | P value | HR (95% CI) | P value | |
| MLKL expression | 7.300 | 0.007 | — | 0.214 |
| p-MLKL expression | 15.430 | <0.001 | 4.500 (1.885, 10.743) | 0.001 |
| Tumor necrosis | 4.815 | 0.028 | — | 0.105 |
| N stage | 16.769 | <0.001 | 8.919 (3.471, 22.917) | <0.001 |
| Clinical stage | 11.978 | 0.001 | — | 0.552 |
| Recurrence | 13.479 | <0.001 | — | 0.745 |
| Lymph node metastasis | 14.824 | <0.001 | — | 0.592 |
| Tumor progression | 19.955 | <0.001 | 4.502 (2.016, 10.054) | <0.001 |
| T stage | 2.315 | 0.128 | — | — |
| Histologic grade | 0.251 | 0.617 | — | — |
| Tumor location | 6.980 | 0.323 | — | — |
| Gender | 0.004 | 0.949 | — | — |
| Age | 0.009 | 0.926 | — | — |
| Tobacco | 0.594 | 0.441 | — | — |
| Alcohol | 1.510 | 0.219 | — | — |
| Areca-nut | 1.303 | 0.254 | — | — |
Bold value indicates p value < 0.05.