Table. 4.
Univariate and multivariate analysis of risk factors for patients’ progression-free survival (PFS).
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| χ2 | P value | HR (95% CI) | P value | |
| MLKL expression | 1.144 | 0.285 | — | — |
| p-MLKL expression | 8.232 | 0.004 | 3.277 (1.534, 7.001) | 0.002 |
| Tumor necrosis | 6.169 | 0.013 | — | 0.501 |
| N stage | 0.005 | 0.946 | — | — |
| Clinical stage | 0.203 | 0.653 | — | — |
| T stage | 0.623 | 0.430 | — | — |
| Histologic grade | 0.282 | 0.596 | — | — |
| Tumor location | 0.072 | 0.789 | — | — |
| Gender | 0.048 | 0.826 | — | — |
| Age | 0.002 | 0.962 | — | — |
| Tobacco | 0.331 | 0.565 | — | — |
| Alcohol | 1.555 | 0.212 | — | — |
| Areca-nut | 7.306 | 0.007 | 2.376 (1.258, 4.490) | 0.008 |
Bold value indicates p value < 0.05.