Table 3.

Systolic function in HCM patients

LV systolic function

1. EF is typically preserved in HCM patients despite significant impairment of longitudinal systolic LV function

2. EF is therefore not adequate to evaluate medical treatment and cardiac transplantation

3. GLS by speckle-tracking echocardiography is an accurate measure of systolic function

4. Speckle-tracking echocardiography reveals subtle changes in systolic function in genotype-positive relatives