Table 4.
The sensitivity and specificity for each MSI microsatellite marker compared with MMR-IHC in 97 colorectal cases
| True poss | False poss | False neg | True neg | Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|---|
| ProDx® MSI | ||||||
| BAT-60 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| BAT-59 | 36 | 2 | 0 | 59 | 100 | 96.7 |
| BAT-56 | 33 | 5 | 3 | 56 | 91.7 | 91.8 |
| BAT-52 | 33 | 3 | 3 | 58 | 91.7 | 95.1 |
| NR-21 | 31 | 1 | 5 | 60 | 86.1 | 98.4 |
| BAT-25 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| BAT-26 | 34 | 1 | 2 | 60 | 94.4 | 98.4 |
| MONO-27 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| MSI 1.2 | ||||||
| NR-21 | 31 | 1 | 5 | 60 | 86.1 | 98.4 |
| NR-24 | 29 | 1 | 7 | 60 | 80.6 | 98.4 |
| BAT-25 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| BAT-26 | 34 | 1 | 2 | 60 | 94.4 | 98.4 |
| MONO-27 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| NCI panel | ||||||
| D5S346 | 16 | 0 | 20 | 61 | 44.4 | 100 |
| D17S250 | 15 | 0 | 21 | 61 | 41.7 | 100 |
| D2S123 | 18 | 1 | 18 | 60 | 50.0 | 98.4 |
| BAT-25 | 33 | 1 | 3 | 60 | 91.7 | 98.4 |
| BAT-26 | 34 | 1 | 2 | 60 | 94.4 | 98.4 |