Table 4.
Pooled analysis of studies comparing PPOS vs GnRH-a short protocols
| Endpoint | Number of events/number of patients, absolute event rate (%) | OR | 95% CI | p | |
|---|---|---|---|---|---|
| PPOS | GnRH-a | ||||
| Congenital malformations | 51/4510 (1.13) | 58/4774 (1.21) | 0.92 | 0.62 to 1.35 | 0.66 |
| Low birth weight | 881/4508 (19.5) | 886/4772 (18.5) | 1.06 | 0.95 to 1.18 | 0.29 |
| Preterm birth | 177/3742 (4.73) | 264/3917 (6.74) | 0.90 | 0.8 to 1.02 | 0.10 |
CI, confidence interval; GnRH-a, gonadotropin-releasing hormone agonist; OR, odds ratio; PPOS, progestin prime ovarian stimulation