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. 2020 May 22;10:8587. doi: 10.1038/s41598-020-65468-1

Table 4.

Elimination half- life (T1/2), peak plasma concentration (Cmax) and total drug exposure (AUC0-∞) of curcumin.

Nanoemulsions/drug T1/2 (h) Cmax (µg) AUC0-∞ (µg.h/ml)
Cur_NE (Oral) 5.8 ± 1.2 27.5 ± 4.5 239.5 ± 7.5
Cur_NE (I.V) 8.5 ± 2.3 37 ± 3.4 304.1 ± 8.4
Cur (Oral) 1.5 ± 0.6 3.1 ± 0.6 12.9 ± 3.5
Cur (I.V) 2.1 ± 0.3 8.8 ± 0.7 21.4 ± 1.2