Table 4.
Hazard ratio for the association between comorbidity index as assessed at diagnosis and outcome in RA
| All-cause mortality | Model C-statistic | Any joint surgery | Model C-statistic | Medium or small joint surgery | Model C-statistic | |
|---|---|---|---|---|---|---|
| CCI unadjusted HR (95% CI; P-value) | 1.53 (1.21–1.93; P < 0.001) | 0.650 | 1.01 (0.94–1.09; P = 0.764) | 0.502 | 0.84 (0.69–1.02; P = 0.073) | 0.541 |
| CCI adjusteda HR (95% CI; P-value) | 1.30 (0.99–1.70; P = 0.057) | 0.814 | 0.94 (0.87–1.01; P = 0.101) | 0.600 | 0.83 (0.68–1.01; P = 0.068) | 0.582 |
| RDCI unadjusted HR (95% CI) | 1.50 (1.20–1.87; P < 0.001) | 0.682 | 1.08 (1.03–1.14; P = 0.002) | 0.542 | 0.96 (0.86–1.08; P = 0.500) | 0.505 |
| RDCI adjusteda HR (95% CI) | 1.26 (1.00–1.59; P = 0.049) | 0.815 | 1.03 (0.97–1.08; P = 0.334) | 0.600 | 0.96 (0.85–1.08; P = 0.461) | 0.568 |
a
Adjusted for age and gender. CCI: Charlson Comorbidity Index; HR: hazard ratio; RDCI: Rheumatic Disease Comorbidity Index.