Table 1.
Associations with inflammatory arthritis development
| All patients (n = 357) | Arthritis (n = 63) | No Arthritis (n = 294) | HRa (95% CI) | P-value | HRb (95% CI) | P-value | HRc (95% CI) | P-value | |
|---|---|---|---|---|---|---|---|---|---|
| MRI features | |||||||||
| Feet (MTP 1–5) | |||||||||
| Tenosynovitis, n (%) | 29 (8) | 17 (27) | 12 (4) | 6.64 | <0.001 | 4.75 | <0.001 | 3.14 | 0.003 |
| (3.79; 1.63) | (2.38; 9.49) | (1.48; 6.64) | |||||||
| Synovitis, n (%) | 34 (10) | 16 (25) | 18 (6) | 4.46 | <0.001 | 2.48 | 0.017 | 2.15 | |
| (2.53; 0.88) | (1.18; 5.23) | (0.98; 4.68) | 0.06 | ||||||
| BMO, n (%) | 21 (6) | 7 (11) | 14 (5) | 2.57 | 0.019 | 0.66 | 0.38 | 0.67 | |
| (1.17; 5.64) | (0.25; 1.69) | (0.25; 1.76) | 0.41 | ||||||
| Hands (MCP 2–5 and wrist) | |||||||||
| Tenosynovitis, n (%) | 95 (27) | 41 (65) | 54 (18) | 6.59 | <0.001 | 6.16 | <0.001 | 5.36 | <0.001 |
| (3.92; 11.08) | (3.58; 10.62) | (3.07; 9.37) | |||||||
| Synovitis, n (%) | 60 (17) | 19 (30) | 41 (14) | 2.35 | 0.002 | 1.06 | 0.85 | 1.12 | 0.69 |
| (1.37; 4.02) | (0.60; 1.87) | (0.63; 2.01) | |||||||
| BMO, n (%) | 57 (16) | 18 (29) | 39 (13) | 2.39 | 0.002 | 1.94 | 0.019 | 2.33 | 0.004 |
| (1.39; 4.14) | (1.11; 3.38) | (1.31; 4.14) | |||||||
| Clinical features | |||||||||
| Elevated CRP, n (%) | 71 (21) | 21 (33) | 50 (18) | 2.22 | 0.003 | ||||
| (1.31; 3.75) | |||||||||
| ACPA and/or RF | 69 (21) | 30 (48) | 39 (14) | 4.37 | <0.001 | ||||
| Positive, n (%) | (2.65; 7.19) |
a
HR of univariable analyses.
b
HR of multivariable analyses including the three inflammatory MRI features; multivariable analyses were performed for the MTP, MCP and wrist separately.
c
Multivariable analyses including also CRP, positivity for ACPA and/or RF.