Table 1.
Distribution of ESBL and AmpC and prevalence of virulence genes in K. pneumoniae isolates
Virulence groups | Virulence genes | ESBL genes | AmpC genes | Phenotypic detection | |||
---|---|---|---|---|---|---|---|
blaCTX-M-14 (n=33) | blaCTX-M-15 (n=61) | blaCMY-2 (n= 37) | blaDHA-1 (n=21) | ESBL production (n=36) | AmpC production (n= 9) | ||
Lipopolysaccharides | uge (n= 57) | 32 | 57 | 34 | 19 | 34 | 8 |
ycfM (n= 56) | 30 | 56 | 34 | 20 | 34 | 9 | |
wabG (n= 54) | 29 | 54 | 33 | 19 | 33 | 7 | |
Adhesins | kpn (n= 28) | 15 | 28 | 4 | 8 | 20 (p=0.05 ) | 7 (p=0.04 ) |
mrkD (n= 17) | 3 | 17 | 12 | 14 (p=0.01 ) | 12 (p=0.04 ) | 0 | |
fimH (n= 11) | 9 (p=0.04 ) | 11 | 7 | 5 | 7 | 0 | |
Iron acquisition systems | iutA (n= 20) | 14 | 20 | 16 (p=0.02 ) | 6 | 14 | 1 |
iroN (n= 4) | 1 | 4 | 4 | 1 | 2 | 0 | |
Enterobactin | entB (n= 58) | 31 | 58 | 37 | 20 | 34 | 7 (p=0.05 ) |
Allantoin metabolism | allS (n= 2) | 1 | 2 | 1 | 1 | 1 | 0 |
Capsule encoding genes | wcaG (n= 17) | 8 | 17 | 11 | 5 | 8 | 1 |
magA (n=0) | 0 | 0 | 0 | 0 | 0 | 0 | |
K2A (n=0) | 0 | 0 | 0 | 0 | 0 | 0 | |
Hypermucoviscosity | rmpA (n=13) | 10 | 13 | 11 (p=0.04 ) | 5 | 12 (p=0.005 ) | 0 |
Toxins | cnf-1 (n=3) | 1 | 3 | 1 | 1 | 1 | 1 |
hly (n= 1) | 1 | 1 | 1 | 0 | 0 | 0 |