Table 1. Comparison between neuroblastoma patients and controls regarding TP53 gene rs1042522 C>G genotypes frequencies in eastern Chinese children.

Genotype	Cases (N=373)	Controls (N=762)	Pa	Crude OR (95% CI)	P	Adjusted OR (95% CI)b	Pb
rs1042522 C>G (HWE = 0.241)
CC	120 (32.17)	233 (30.58)		1.00		1.00
CG	184 (49.33)	391 (51.31)		0.91 (0.69–1.21)	0.530	0.92 (0.70–1.22)	0.567
GG	69 (18.50)	138 (18.11)		0.97 (0.68–1.40)	0.873	0.99 (0.69–1.42)	0.947
Additive			0.782	0.98 (0.82–1.17)	0.782	0.98 (0.82–1.18)	0.855
Dominant	253 (67.83)	529 (69.42)	0.586	0.93 (0.71–1.21)	0.586	0.94 (0.72–1.23)	0.639
Recessive	304 (81.50)	624 (81.89)	0.874	1.03 (0.75–1.41)	0.873	1.04 (0.75–1.43)	0.814

Abbreviations: CI, confidence interval, HWE, Hardy–Weinberg equilibrium; OR, odds ratio.

^aχ² test for genotype distributions between neuroblastoma patients and controls.

^bAdjusted for age and gender.