Table 2. TP53 gene rs1042522 C>G polymorphism and neuroblastoma susceptibility stratified by demographic characteristics in eastern Chinese children.
Variables | Cases/Controls | Crude OR | P | Adjusted ORa | Pa | |
---|---|---|---|---|---|---|
CC | CG/GG | (95% CI) | (95% CI) | |||
Age, month | ||||||
≤18 | 53/115 | 110/225 | 1.06 (0.71–1.58) | 0.772 | 1.06 (0.71–1.57) | 0.786 |
>18 | 67/118 | 143/304 | 0.83 (0.58–1.19) | 0.305 | 0.83 (0.58–1.19) | 0.311 |
Gender | ||||||
Females | 46/105 | 120/235 | 1.17 (0.77–1.76) | 0.464 | 1.21 (0.80–1.83) | 0.375 |
Males | 74/128 | 133/294 | 0.78 (0.55–1.11) | 0.172 | 0.77 (0.54–1.10) | 0.154 |
Sites of origin | ||||||
Adrenal gland | 36/233 | 58/529 | 0.71 (0.46–1.11) | 0.129 | 0.72 (0.46–1.12) | 0.148 |
Retroperitoneal | 46/233 | 99/529 | 0.95 (0.65–1.39) | 0.784 | 0.95 (0.65–1.40) | 0.801 |
Mediastinum | 34/233 | 76/529 | 0.99 (0.64–1.52) | 0.944 | 1.00 (0.65–1.54) | 0.985 |
Others | 4/233 | 20/529 | 2.20 (0.74–6.51) | 0.154 | 2.37 (0.80–7.04) | 0.121 |
Abbreviations: CI, confidence interval; OR, odds ratio.
Adjusted for age and gender, omitting the corresponding stratification factor.