Table 2.
Characteristics of the study group.
| Sarcoidosis | HP | CG | |
|---|---|---|---|
| Number of subjects | 144 | 18 | 11 |
| Age (mean) | 46 | 49 | 52 |
| Gender: female (%)/male (%) | 28/72 | 41/59 | 36/64 |
| Smokers (%)/ex-smokers (%)/non-smokers (%) | 6/22/74 | 6/33/61 | 9/9/82 |
| Stage: I/II/III/IV (%) (sarcoidosis) | 45/52/2/1 | ||
| Lӧfgren syndrome: Yes/no (%) | 29/71 | ||
| Clinical presentation: Inflammatory/fibrotic (%) (HP) | 57/43 | ||
| Specific IgG antibodies: positive/negative (%) | — | 38∗/62 | — |
| Occupational anamnesis: positive/negative (%) | 62∗∗/38 | ||
| Diffusing capacity of lungs for carbon monoxide (DLCO) (%; mean) | 88 ± 16 | 60 ± 16 | 88 ± 17 |
| Lymphocytes (%; mean) in BALF | 37 ± 19 | 66 ± 19 | 8 ± 4 |
| Lymphocytes (total number; mean) in BALF | 56 ± 51 | 258 ± 171 | 5 ± 4 |
| CD3 (%; mean) in BALF | 92 ± 6 | 85 ± 13 | 81 ± 7 |
| CD3 (total number; mean) in BALF | 52 ± 49 | 231 ± 165 | 4 ± 3 |
| CD4 (%; mean) in BALF | 70 ± 15 | 43 ± 27 | 50 ± 11 |
| CD4 (total number; mean) in BALF | 41 ± 40 | 114 ± 112 | 3 ± 2 |
| CD8 (%; mean) in BALF | 22 ± 12 | 45 ± 29 | 29 ± 7 |
| CD8 (total number; mean) in BALF | 10 ± 11 | 115 ± 125 | 2 ± 1 |
| CD4/CD8 | 5.1 ± 4.5 | 2.9 ± 4.2 | 1.8 ± 0.7 |
∗Cladosporidium, Thermoactinomyces vulgaris, Absidia corymbifera, Micropolyspora faeni, Actinomyces vulgaris, Aspergillus nidulans, Aspergillus niger; ∗∗farmers: 2x, animal feeding: 2x, bird breeders: 2x, textile workers: 1x, chemical industry: 5x, wood workers: 1x; CD3–T cells, CD4–T-helper cells, CD8–cytotoxic T cells; total number–total number of cells per microliter.