Table 2.
Comparison of baseline clinic-pathological characteristics based on PD-1 and Tim-3 expressions of CRC patients in TCGA cohort.
| Cases (no.(%)) | PD-1 | Tim-3 | |||||
|---|---|---|---|---|---|---|---|
| High (no.(%)) | χ 2 (Fisher) | P | High (no.(%)) | χ 2 (Fisher) | P | ||
| Age(years) | 10.413 | <0.001 | 0.102 | 0.812 | |||
| ≤60 | 112(29.63) | 26(23.21) | 36(32.14) | ||||
| >60 | 266(70.37) | 108(40.60) | 90(33.83) | ||||
| Gender | 0.632 | 0.668 | 1.530 | 0.231 | |||
| Male | 194(51.32) | 71(36.60) | 59(30.41) | ||||
| Female | 184(48.68) | 63(34.24) | 67(36.41) | ||||
| Primary site | 11.410 | 0.003 | 11.354 | 0.003 | |||
| Right hemicolon | 162(42.86) | 71(43.83) | 69(43.59) | ||||
| Left hemicolon | 109(28.83) | 26(23.85) | 31(28.44) | ||||
| Rectum | 107(28.31) | 37(34.60) | 26(24.30) | ||||
| T stage | 0.156 | 0.984 | 4.126 | 0.248 | |||
| T1 | 13(3.44) | 4(30.77) | 2(15.38) | ||||
| T2 | 83(21.96) | 29(34.94) | 23(27.71) | ||||
| T3 | 260(68.78) | 93(35.77) | 92(35.38) | ||||
| T4 | 22(5.82) | 8(36.36) | 9(40.91) | ||||
| N stage | 1.441 | 0.248 | 0.742 | 0.413 | |||
| N0 | 259(68.52) | 97(37.45) | 90(34.75) | ||||
| N+ | 119(31.48) | 37(31.09) | 36(30.25) | ||||
| Clinical stage | 1.454 | 0.483 | 4.815 | 0.090 | |||
| I | 87(23.02) | 33(37.93) | 23(26.44) | ||||
| II | 172(45.50) | 64(37.21) | 67(39.41) | ||||
| III | 119(31.48) | 37(31.09) | 36(30.25) | ||||
| Histological type | 0.221 | 0.620 | 3.292 | 0.088 | |||
| Adenocarcinoma | 334(88.36) | 117(35.03) | 106(31.74) | ||||
| Mucinous | 44(11.64) | 17(38.64) | 20(45.45) | ||||
| Total | 378(100) | 134(35.45) | 126(33.33) | ||||