. 2020 May 14;2020:6961348. doi: 10.1155/2020/6961348

Table 1.

Echocardiographic analysis of male and female OVE26 and FVB mice. IVS; D, LVID; D, LVPW; D, IVS; S, LVID; S, LVPW; S, LV Vol; D, LV Vol; S, EF, FS, LV Mass, LV Mass corrected. N ≥ 6 in each group ∗ vs. sex- and age-matched FVB, P < 0.05; ∗∗ vs. sex- and age-matched FVB, P < 0.01; ^# vs. male, P < 0.05, ^## vs. male, P < 0.01.

Age	Sex	Genotype	IVS; d (mm)	LVID; d (mm)	LVPW; d (mm)	IVS; s (mm)	LVID; s (mm)	LVPW; s (mm)
4 weeks old	Male	FVB	0.55 ± 0.03	3.21 ± 0.29	0.6 ± 0.03	0.8 ± 0.07	1.77 ± 0.21	0.84 ± 0.09
	Male	OVE26	0.55 ± 0.06	3.19 ± 0.32	0.59 ± 0.04	0.79 ± 0.09	1.71 ± 0.25	0.84 ± 0.1
	Female	FVB	0.56 ± 0.04	3.39 ± 0.17	0.65 ± 0.08	0.86 ± 0.05	1.86 ± 0.14	0.97 ± 0.07##
	Female	OVE26	0.55 ± 0.04	3.19 ± 0.25∗	0.62 ± 0.08	0.83 ± 0.08	1.73 ± 0.19	0.88 ± 0.09∗

12 weeks old	Male	FVB	0.62 ± 0.02	3.77 ± 0.31	0.68 ± 0.03	0.86 ± 0.07	2.19 ± 0.23	0.97 ± 0.11
	Male	OVE26	0.61 ± 0.02	3.88 ± 0.25	0.7 ± 0.05	0.86 ± 0.07	2.25 ± 0.19	1.02 ± 0.1
	Female	FVB	0.61 ± 0.03	3.64 ± 0.2	0.68 ± 0.04	0.86 ± 0.07	2.05 ± 0.16	0.97 ± 0.1
	Female	OVE26	0.62 ± 0.03	3.73 ± 0.24	0.72 ± 0.05	0.89 ± 0.06∗	2.12 ± 0.17	1.01 ± 0.1

24 weeks old	Male	FVB	0.6 ± 0.02	4 ± 0.15	0.71 ± 0.03	0.89 ± 0.05	2.46 ± 0.15	1.04 ± 0.08
	Male	OVE26	0.62 ± 0.02	4.04 ± 0.19	0.71 ± 0.03	0.86 ± 0.03∗	2.69 ± 0.16∗∗	1 ± 0.07
	Female	FVB	0.61 ± 0.02	3.94 ± 0.23	0.72 ± 0.03	0.86 ± 0.06	2.4 ± 0.16	1.08 ± 0.06
	Female	OVE26	0.6 ± 0.02	4.01 ± 0.13	0.73 ± 0.04	0.88 ± 0.04	2.55 ± 0.11∗#	1 ± 0.05∗∗

36 weeks old	Male	FVB	0.63 ± 0.02	4.09 ± 0.13	0.72 ± 0.03	0.92 ± 0.03	2.52 ± 0.11	1.05 ± 0.08
	Male	OVE26	0.6 ± 0.01∗	4.13 ± 0.22	0.7 ± 0.03	0.85 ± 0.04∗∗	2.79 ± 0.17∗∗	1.03 ± 0.06
	Female	FVB	0.61 ± 0.04	3.9 ± 0.16#	0.72 ± 0.05	0.87 ± 0.06	2.36 ± 0.12#	1.04 ± 0.07
	Female	OVE26	0.6 ± 0.01	4.09 ± 0.09∗	0.72 ± 0.03	0.83 ± 0.04	2.74 ± 0.12∗∗	1.01 ± 0.03

Age	Sex	Genotype	LV Vol; d (ul)	LV Vol; s (ul)	% EF	% FS	LV mass (mg)	LV mass corrected (mg)

4 weeks old	Male	FVB	41.94 ± 8.87	9.57 ± 2.63	77.43 ± 3.31	44.98 ± 3.11	52.69 ± 8.62	42.15 ± 6.89
	Male	OVE26	41.22 ± 9.55	8.85 ± 3.01	79 ± 4.27	46.6 ± 4.17	51.84 ± 9.97	41.48 ± 7.98
	Female	FVB	47.27 ± 5.45	10.67 ± 2	77.46 ± 2.97	45.18 ± 2.88	61.6 ± 7.17	49.28 ± 5.73#
	Female	OVE26	41.18 ± 7.86	9.01 ± 2.72	78.42 ± 3.01	45.92 ± 2.81	53.41 ± 10.33	42.73 ± 8.27∗

12 weeks old	Male	FVB	61.2 ± 11.85	16.33 ± 4.2	73.62 ± 2.5	41.92 ± 2.05	81.26 ± 12.75	65.01 ± 10.2
	Male	OVE26	65.33 ± 9.46	17.41 ± 3.51	73.55 ± 2.3	41.95 ± 1.91	85.76 ± 10.98	68.61 ± 8.79
	Female	FVB	56.14 ± 7.45	13.76 ± 2.77	75.63 ± 2.53	43.63 ± 2.2	75.79 ± 10.17	60.63 ± 8.13
	Female	OVE26	59.69 ± 8.83	14.9 ± 2.97	75.18 ± 2.05	43.28 ± 1.78	83.08 ± 11.26	66.46 ± 9.01

24 weeks old	Male	FVB	70 ± 6.38	21.5 ± 3.2	69.41 ± 2.26	38.56 ± 1.74	90.9 ± 7.71	72.72 ± 6.17
	Male	OVE26	71.72 ± 7.81	26.82 ± 3.72∗∗	62.7 ± 2.36∗∗	33.47 ± 1.65∗∗	93.14 ± 8.41	74.51 ± 6.72
	Female	FVB	67.99 ± 9.22	20.41 ± 3.21	70.06 ± 1.89	39.04 ± 1.49	90.47 ± 10.96	72.38 ± 8.77
	Female	OVE26	70.48 ± 5.27	23.61 ± 2.52∗∗#	66.54 ± 2.12∗∗##	36.31 ± 1.61∗∗##	92.87 ± 7.06	74.29 ± 5.65

36 weeks old	Male	FVB	73.89 ± 5.28	22.83 ± 2.34	69.17 ± 1.37	38.42 ± 1.05	97.38 ± 6.93	77.91 ± 5.55
	Male	OVE26	76.06 ± 9.26	29.52 ± 4.14∗∗	61.22 ± 2.25∗∗	32.48 ± 1.61∗∗	95.6 ± 7.82	76.48 ± 6.26
	Female	FVB	66.16 ± 6.35#	19.35 ± 2.34#	70.76 ± 2.1	39.59 ± 1.73	88.67 ± 12.53#	70.94 ± 10.03#
	Female	OVE26	74.01 ± 3.83∗	28.17 ± 3.2∗∗	61.99 ± 3.12∗∗	33.03 ± 2.23∗∗	94.5 ± 2.73	75.6 ± 2.18