Table 5.
Univariable Logistic Regression for Death in Patients With Severe Dengue
| Covariate | n | OR (95% CI; P Value)a |
|---|---|---|
| Female gender | 180 | 1.77 (0.87–3.62; .12) |
| Severe bleed | 180 | 3.51 (1.68–7.31; .00081) |
| Severe leak | 180 | 2.28 (1.03–5.02; .042) |
| Severe organ involvement | 180 | 23.57 (5.47–101.62; <.0001) |
| Hepatomegaly | 151 | 2.89 (1.27–6.57; .012) |
| Age at hospitalization (5 years)b | 180 | 1.20 (1.06–1.35; .0043) |
| APACHE II scorec | 178 | 1.33 (1.21–1.45; <.0001) |
| SAPS II scorec | 178 | 1.15 (1.10–1.20; <.0001) |
| SOFA scorec | 178 | 1.84 (1.53–2.21; <.0001) |
| Peak aspartate aminotransferase (U/L)d | 176 | 2.92 (2.07–4.12; <.0001) |
| Peak alanine aminotransferase (U/L)d | 179 | 3.36 (2.28–4.95; <.0001) |
| Peak lactate dehydrogenase (U/L)d | 173 | 5.80 (3.37–9.98; <.0001) |
| Peak ferritin (log μg/L)d | 76 | 2.54 (1.38–4.68; .0028) |
| Peak triglycerides (log mmol/L)d | 63 | 0.73 (0.29–1.86; .51) |
| Lowest fibrinogen (log g/L)e | 36 | 3.34 (0.53–21.03; .20) |
| Lowest platelets (log ×109/L)e | 179 | 1.86 (1.30–2.65; .00068) |
| Peak creatinine (log μmol/L)d | 180 | 31.93 (11.21–91.01; <.0001) |
Abbreviations: APACHE, Acute Physiology, Age, Chronic Health Evaluation; CI, confidence interval; OR, odds ratio; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.
aCalculated using logistic regression.
bOR for a 5-year increase.
cOR for a 1-unit increase.
dOR for a 1-unit increase in the natural logarithm.
eOR for a 1-unit decrease in the natural logarithm.