Figure 2.

Trajectories of behavioral outcomes during and following direct-acting antiviral treatment for hepatitis C virus infection among people with recent injection drug use or receiving opioid agonist treatment recruited and followed in SIMPLIFY and D3FEAT (N = 190). Solid lines represent the estimated probability of each behavioral outcome for each group, and dashed lines represent 95% confidence intervals. Behaviors refer to the past month period. Baseline visit refers to the date of treatment initiation. Follow-up periods 1, 2, and 3 correspond to weeks 60, 84, and 108 since treatment initiation, respectively. At screening, the sample size was 188 rather than 190 because behavioral data were unavailable for 2 participants recruited in D3FEAT. Example of interpretation: for stimulant injecting, 22% of participants injected stimulants at nearly all visits, 18% oscillated between injecting and noninjecting patterns, and 60% never injected. Abbreviations: BL, baseline; AUDIT-C, Alcohol Use Disorders Identification Test–Consumption; BL, baseline; ETR, end of treatment; FU, follow-up; SCR, screening; SVR, sustained virological response; W, week.