Table 1.
Characteristic | Total | Oseltamivir | Placebo |
---|---|---|---|
(N =; 556) | (n =; 277) | (n =; 279) | |
Age, y | |||
Median (quartiles) | 36 (27, 47) | 37 (27, 49) | 35 (27, 46) |
Min, Max | 18, 64 | 18, 64 | 18, 63 |
Sex | |||
Female | 347 (62%) | 183 (66%) | 164 (59%) |
Race | |||
Asian | 385 (69%) | 193 (70%) | 192 (69%) |
White | 150 (27%) | 74 (27%) | 76 (27%) |
Black or African American | 18 (3%) | 7 (3%) | 11 (4%) |
Race not available | 3 (1%) | 3 (1%) | 0 |
Ethnicity | |||
Hispanic or Latino | 24 (4%) | 11 (4%) | 13 (5%) |
Country | |||
Thailand | 366 (66%) | 182 (66%) | 184 (66%) |
United States | 178 (32%) | 91 (33%) | 87 (31%) |
Argentina | 12 (2%) | 4 (1%) | 8 (3%) |
Influenza type (site testing) | |||
A | 387 (70%) | 187 (68%) | 200 (72%) |
B | 164 (29%) | 88 (32%) | 76 (27%) |
Coinfection with more than 1 virus | 5 (1%) | 2 (1%) | 3 (1%) |
Influenza type (central laboratory) | |||
Influenza A/H3N2 | 251 (45%) | 122 (44%) | 129 (47%) |
Influenza A/H1N1 | 93 (17%) | 39 (14%) | 54 (19%) |
Influenza B | 156 (28%) | 85 (31%) | 71 (26%) |
Negative | 52 (9%) | 30 (11%) | 22 (8%) |
Coinfectiona | 1 (<0.5%) | 0 (0%) | 1 (<0.5%) |
No. missing | 3 | 1 | 2 |
Hours from onset of influenza-like illness to screening | |||
Median (quartiles) | 28 (21, 39) | 29 (22, 40) | 27 (20, 37) |
Min, Max | 0, 49 | 1, 49 | 0, 49 |
Hours from screening to randomization | |||
Median (quartiles) | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) |
Min, Max | 0, 23 | 0, 23 | 0, 10 |
Hours from randomization to treatment initiation | |||
Median (quartiles) | 1 (0, 5) | 1 (0, 5) | 1 (0, 5) |
Min, Max | 0, 21 | 0, 20 | 0, 21 |
Smoking (at any point)? | |||
Yes | 68 (12%) | 35 (13%) | 33 (12%) |
Influenza vaccination in the season of enrollment? | |||
Yes | 57 (10%) | 34 (12%) | 23 (8%) |
aCoinfection: quantitative polymerase chain reaction (qPCR) results are for flu A/H3 as flu B was not detected by qPCR.