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. Author manuscript; available in PMC: 2020 May 23.
Published in final edited form as: Int Forum Allergy Rhinol. 2019 Jun 28;9(9):993–999. doi: 10.1002/alr.22366

Figure 1. Neuronal organization and olfactory function remain intact in mice with OSN-specific Bmi1-KO.

Figure 1.

(A and B) Gene expression analysis and immunofluorescence of BMI1, ****p<0.0001, n=5.

(C) Measurements of OE thickness, p=0.854, n=4.

(D) Representative immunofluorescence of OMP, a marker for mature OSNs, and GAP43, a marker for immature OSNs.

(E) Average traces of electro-olfactogram recordings from all animals in control vs. Bmi1-KO group. Solid black line at the top of the panel indicates the timing of 0.1M amyl acetate stimulation for a duration of 0.1 seconds, n=5.

(F) Average of mean peak EOG responses per animal, p=0.234, n=5.

Dotted lines in B and C mark the basal lamina, bar is 25μm.