Table 5.

HRs (95% CI) for overall mortality, cardiovascular mortality, non-fatal and fatal stroke, and non-fatal myocardial infarction or coronary death in dependence on proinsulin to insulin ratio (per SD)

	All-cause mortality	Cardiovascular mortality	Non-fatal or fatal stroke, myocardial infarction, or coronary death
n (non-cases)†	1391	1459	1262
n (cases)‡	123	55	93
Without adjustment
Total study cohort	1.57 (1.31 to 1.88)***	1.74 (1.33 to 2.27)***	1.33 (1.09 to 1.63)**
Adjustment for sex, age, BMI, arterial hypertension, physical activity (model 3)
Total study cohort	1.16 (0.96 to 1.42)	1.22 (0.90 to 1.64)	1.01 (0.81 to 1.26)

**p<0.01; ***p<0.001.

†Number of participants without events.

‡Number of events.

BMI, body mass index.