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. 2020 May 19;8(1):e001009. doi: 10.1136/bmjdrc-2019-001009

Figure 1.

Figure 1

Characteristic of thermosensitive hydrogel. (A) Control release profile of FGF-21, KGF-2 and KGF-2/FGF-21 mixtures loaded hydrogel compared with that of corresponding protein in 0.9% saline respectively (n=3). ‘a, b, c’ indicated as significantly different from corresponding protein in 0.9% saline respectively (p<0.01). (B) Gelation of thermosensitive hydrogel. (C) Storage modulus and loss modulus of thermosensitive hydrogel. (D) SEM images of thermosensitive hydrogel (scale bars, 50 µm). (E) Skin wound of GK rat (scales 0.2 cm per square). (F) Wound healing rate. compared with the control group, *p<0.05, **p<0.01, ***p<0.001 (n=7 on day 7, n=6 on day 14, n=6 on day 25, n=3 on day 31). FGF-21, fibroblast growth factor-21; F21–K2, FGF-21 and KGF-2; GK, Goto-Kakizaki; KGF-2, keratinocyte growth factor-2; SEM, scanning electron microscope.