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. 2020 May 19;13:4365–4372. doi: 10.2147/OTT.S247796

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© 2020 Shi et al.

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Stability of circRNAs under extreme conditions. (A) incubation at 4, −20, and −80°C for 4 h; (B) digestion with RNase A for 2 h and 4 h; (C) freeze thaw cycles repeatedly; and (D) acidic or alkaline conditions.