Table 2.

Capacity of Two circRNAs Discriminating PTC from HC

circRNA	Training Cohort			Test Cohort
	circRAPGEF5	hsa_circ_0058124	Combination of circRNAs	circRAPGEF5	hsa_circ_0058124	Combination of circRNAs
AUC	0.711 (0.597–0.824)	0.790 (0.692–0.887)	0.860 (0.784–0.937)	0.692 (0.577–0.807)	0.727 (0.609–0.844)	0.867 (0.787–0.947)
Sensitivity	0.647	0.810	0.805	0.722	0.719	0.866
Specificity	0.754	0.618	0.749	0.631	0.710	0.695
Youden index	0.401	0.428	0.554	0.353	0.429	0.561
Cutoff	11.25	8.78	13.77	11.25	8.78	13.77

Abbreviations: PTC, papillary thyroid cancer; HC, healthy control; AUC, area under curve.