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. 2020 May 19;13:4373–4384. doi: 10.2147/OTT.S247491

Figure 1.

Figure 1

Positive FAM110B expression correlated with early TNM staging and favorable prognosis of NSCLC patients. Differential mRNA expression of FAM110B in normal and cancerous tissues from GEPIA database (LUAD, adenocarcinoma; LUSC, lung squamous cell carcinoma; (A) survival curves of patients with low or high FAM110B mRNA expression from KMplotter database (B), representative figures of positive FAM110B expression in normal bronchial epithelium (C), positive and negative FAM110B in lung squamous cell carcinoma (D, E), positive and negative FAM110B in lung adenocarcinoma (F, G), Positive FAM110B expression in normal bronchial epithelium with negative FAM110B expression in adjacent squamous cell carcinoma (H), (C–H), magnification, 200×, scale bar = 50μm. Kaplan–Meier survival curves of patients with or without FAM110B expression (I). Western blotting results in clinical NSCLC tissue samples and in paired noncancerous tissue samples (J). Western blotting results in human bronchial epithelial cell line (HBE) and in NSCLC cell lines (A549, H1299, H460, PC9 and LK2 (K). Immunofluorescence results in A549, H1299 and LK2 cells (L). *P < 0.05.