Table 1.
Biological properties of primary AML samples. A summary of the main biological properties of primary AML samples used in this study.
| USP7 expression | ||||||
|---|---|---|---|---|---|---|
| Total | Low (<median value) | High (>median value) | P value | |||
| n | n | |||||
| Age in years, mean ± SD, n = 46 | 56.26 ± 17.69 | 23 | 56.00 ± 20.58 | 23 | 56.52 ± 14.71 | 0.922 |
| White blood cells in g/liter, mean ± SEM, n = 44 | 62.81 ± 10.92 | 21 | 44.07 ± 12.63 | 23 | 79.94 ± 16.90 | 0.101 |
| Total | n | % | n | % | P value | |
| Gender, n (%) | 0.750 | |||||
| Male | 32 (69.6) | 17 | (73.9) | 15 | (65.2) | |
| Female | 14 (30.4) | 6 | (26.1) | 8 | (34.8) | |
| Secondary AML, n (%) | 0.021 | |||||
| No | 38 (88.4) | 16 | (76.2) | 22 | (100) | |
| Yes | 5 (11.6) | 5 | (23.8) | 0 | (0) | |
| Cytogenetic risk, n (%) | 0.114 | |||||
| Favorable | 6 (13.0) | 4 | (17.4) | 2 | (8.7) | |
| Intermediate | 37 (80.4) | 16 | (69.6) | 21 | (91.3) | |
| Adverse | 3 (6.5) | 3 | (13.0) | 0 | (0) | |
| NPM1 mutation, n (%) | >0.999 | |||||
| No | 22 (51.2) | 10 | (50) | 12 | (52.2) | |
| Yes | 21 (48.3) | 10 | (50) | 11 | (47.8) | |
| FLT3-ITD mutation, n (%) | 0.003 | |||||
| No | 25 (56.8) | 17 | (80.9) | 8 | (34.8) | |
| Yes | 19 (43.2) | 4 | (19.0) | 15 | (65.2) | |
Statistical analysis was established by the unpaired t-test for age and white blood cell count and then a Fisher’s exact tests were applied to determine the P value.